Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream, Refillable — 21 Peptides & Deep Hydration

Peter Thomas Roth Peptide Skinjection™ Moisture Infusion Cream is a refillable, peptide-rich moisturizer designed to visibly plump skin, improve firmness and supply long-lasting hydration without needles.

This lightweight yet intensely hydrating cream combines 21 amplified peptides and neuropeptides with skin-nourishing humectants to help restore the look of youthful bounce. Formulated to target the appearance of expression lines, loss of elasticity and surface texture, it also includes Gamma Proteins to support radiance and even tone. Fast-absorbing and refillable, the moisturizer delivers a concentrated peptide complex alongside squalane, hyaluronic acid, cactus flower extract and trehalose for a dewy, supple finish.

How quickly will I notice reduced expression lines?

Many users report a visible softening of expression lines in a short timeframe when used consistently. Results vary by individual, but a consumer perception study noted changes within one week of regular application.

• Contains 21 amplified peptides and neuropeptides that target expression lines.
• Formulated for daily use—apply morning and night for best results.
• Lightweight texture encourages consistent application and absorption.

What ingredients lock in moisture without feeling heavy?

This formula blends multiple humectants and emollients to hydrate, plump and smooth without a greasy residue. Hyaluronic acid draws in moisture while squalane and trehalose support skin barrier function for longer-lasting softness.

• Hyaluronic Acid hydrates deeply and instantly improves surface plumpness.
• Squalane provides lightweight, non-comedogenic emollience.
• Cactus Flower and trehalose add botanical hydration and protect against moisture loss.

Why is the refillable design important for skincare routines?

The refillable jar minimizes waste and supports a sustainable routine without sacrificing performance. You get the same concentrated peptide complex with less packaging over time, making it economical for regular users.

• Refillable format reduces single-use plastic and overall packaging waste.
• Compatible refills keep product freshness and potency between purchases.
• Maintains a premium dosing experience while lowering long-term cost per use.

Can this cream be layered with other treatments like serums or SPF?

Yes—its lightweight, fast-absorbing texture makes it a flexible mid- or final-step moisturizer in most routines. Apply serums first, follow with this cream, then finish with sunscreen in the morning.

• Works well over peptide serums, antioxidants and moisturizers.
• Non-greasy finish supports makeup application after morning use.
• Use nightly with actives as tolerated; always apply SPF during daytime routines.

Who is this for: Peter Thomas Roth Peptide Skinjection™ Moisture Infusion Cream is aimed at anyone wanting to improve the look of firmness, reduce the appearance of expression lines and boost hydration without heavy textures or injections. It suits normal to dry skin types and those seeking a peptide-forward, sustainable refill option to integrate into daily anti-aging and hydration-focused regimens.

Ingredients

Water/Aqua/Eau, Glycerin, Dimethicone, Olive Oil Decyl Esters, Glycereth-26, Squalane, Butylene Glycol, Behenyl Alcohol, Polysilicone-11, Batyl Alcohol, Cetyl Alcohol, Simmondsia Chinensis (Jojoba) Seed Oil, Hexapeptide-11, Acetyl Hexapeptide-1, Tripeptide-10 Citrulline, Palmitoyl Dipeptide-10, Palmitoyl Hexapeptide-12, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Palmitoyl Tetrapeptide-7, Tripeptide-1, Acetyl Dipeptide-1 Cetyl Ester, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Hyaluronate, Cereus Grandiflorus (Cactus) Flower Extract, Squalene, Phytosterols, Trehalose, Silanetriol Trehalose Ether, Biotin, Citric Acid, Lecithin, Sodium Lactate, Hydrogenated Lecithin, Caprylyl Glycol, Sorbic Acid, Mannitol, Amidinobenzyl Benzylsulfonyl D-Seryl Homophenylalaninamide Acetate, Potassium Sorbate, Sodium Benzoate, Glyceryl Stearate, Caprylic/Capric Triglyceride, Leuconostoc/Radish Root Ferment Filtrate, Sodium Hydroxide, Dimethyl Isosorbide, Potassium Hydrolyzed Polygamma-Glutamate, Laureth-12, Laureth-3, Dextran, Tocopherol, Hydroxyethylcellulose, Disodium Phosphate, Sodium Polyglutamate, Ethylhexylglycerin, Sodium Stearoyl Glutamate, Polyglyceryl-10 Myristate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polysorbate 20, Carbomer, Triethanolamine, Sodium Phosphate, Acrylates Copolymer, Mica, Stearyl Alcohol, Phenoxyethanol.