Perricone MD High Potency Hyaluronic Hydrating Serum, 2 fl oz — 4+2 Hyaluronic Complex, Niacinamide & DMAE for Plumping

Perricone MD High Potency Hyaluronic Intensive Hydrating Serum is a fast‑absorbing facial serum that delivers immediate and long‑lasting hydration using a multi‑form hyaluronic acid complex to help skin look plumper and smoother.

This lightweight serum combines four molecular forms of hyaluronic acid plus two natural hyaluronic building blocks to target moisture at multiple skin layers. Formulated with niacinamide and DMAE alongside the Hyaluronic 4+2 Complex, the product aims to support the skin’s moisture barrier, increase the feel of skin cushion, and reduce the visible appearance of fine lines and surface texture. It’s intended for daily use under moisturizer and works best when applied to damp skin for optimal absorption.

How does this serum deliver visible hydration quickly?

The Hyaluronic 4+2 Complex blends different sizes of hyaluronic molecules so some sit on the surface for instant smoothing while smaller molecules help attract and retain moisture deeper within the skin. This multi‑tier approach supports both immediate plumping and sustained hydration over time. Lightweight siliceless texture absorbs rapidly without leaving a greasy film.

• Four hyaluronic acid forms plus two natural building blocks for layered moisture
• Fast absorption that smooths skin texture and reduces roughness
• Designed to be applied to damp skin to maximize uptake

Will this serum help firm and improve skin texture?

In addition to hyaluronic technology, the formula contains DMAE, known for its tightening effect on skin feel, and niacinamide, which supports an even surface and visible refinement. Regular use can enhance the perceived cushioning of skin and help reduce the look of fine lines by improving hydration and surface clarity. Results depend on consistent application and overall skin condition.

• DMAE provides a lifting sensation to improve the feel of firmness
• Niacinamide helps even tone and supports barrier resilience
• Hydration-driven plumping minimizes the look of fine lines

How should I use this serum in my daily skin routine?

Apply morning and evening after cleansing and while your skin is still slightly damp to lock in moisture. Massage a few drops onto face and neck with upward motions, then follow with your favorite Perricone MD moisturizer or sunscreen in the morning. Its lightweight profile makes it easy to layer with other treatments and makeup.

• Use on damp skin for best absorption and hydration retention
• Apply morning and night before moisturizer or sunscreen
• Compatible with most topical treatments—layer as needed

What can I realistically expect and how quickly?

Many users report immediate smoothing and increased skin softness after the first application due to surface‑level hyaluronic action. Clinical data for the formula indicate hydration benefits lasting multiple days and improvements in barrier function with continued use, though visible lifting and texture improvements build over weeks. Maintain regular use for sustained results; individual response varies.

• Noticeable softness and surface smoothing quickly after application
• Sustained hydration with repeated use; barrier support over weeks
• Visible texture refinement increases with consistent application

Who this is for: This serum is suited for anyone seeking immediate and lasting hydration, especially those with dry or dehydrated skin, early loss of volume, or fine lines. It’s appropriate for most skin types looking to boost moisture, improve skin cushion, and create a smoother base for makeup or subsequent skincare. Avoid if you have specific sensitivities to formula components; patch test if concerned.

Ingredients

Water/Aqua/Eau, Dimethicone, Butylene Glycol, Niacinamide, Acetyl Glucosamine, Squalane, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysilicone-11, Cetearyl Olivate, HDI/Trimethylol Hexyllactone Crosspolymer, Polyisobutene, Sorbitan Olivate, Dimethyl Isosorbide, Polysorbate 20, 1,2-Hexanediol, Caprylyl Glycol, Dimethyl MEA, Hydroxyacetophenone, Citric Acid, Ceramide NP, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Sodium Gluconate, Spermidine, Silica, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Phenoxyethanol, Phytosphingosine, Sodium Hyaluronate Crosspolymer, Hyaluronic Acid, Ethylhexylglycerin, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Glycerin, Disodium Acetyl Glucosamine Phosphate, Sodium Glucuronate, Magnesium Sulfate