Obagi Medical Obagi360 Retinol 1.0 Night Treatment, 1 oz — High‑Strength Retinol with Entrapped Delivery for Smoother Texture

Obagi360 Retinol 1.0 is a dermatologist-tested retinol cream formulated with an entrapped delivery system to help reduce the visible signs of aging while minimizing irritation.

This 1 oz formula from Obagi Medical combines a high-concentration retinol with a controlled-release technology to smooth texture, even skin tone, and target fine lines. Designed for regular use in an evening routine, the entrapped retinol system releases active ingredients gradually to improve tolerability and support visible improvements in skin appearance.

How quickly will I notice results with Obagi360 Retinol 1.0?

Individual responses vary, but clinical testing from the brand reported measurable improvements in facial appearance and texture within weeks for many users. Expect subtle changes first, with progressively clearer benefits after consistent nightly application.

• Clinical data: many users reported improvement in 3 weeks (data on file at Obagi Cosmeceuticals LLC).
• Initial effects: improved skin texture and smoother-feeling skin after several applications.
• Continued use: greater reduction in fine lines and more even tone over months.

How do I incorporate this retinol into my skincare routine?

Use Obagi360 Retinol 1.0 in the evening after cleansing and before moisturizer, starting slowly to assess tolerance. Pair it with SPF during daytime—retinoids can increase sun sensitivity— and avoid simultaneous use with other strong actives until your skin adapts.

• Start: apply a pea-sized amount 2–3 times weekly, then increase frequency.
• Layering: allow absorbent serums to dry before retinol; finish with a gentle night moisturizer.
• Sun protection: apply broad-spectrum sunscreen every morning while using retinol.

Will this product cause irritation or dryness?

The entrapped retinol delivery system is designed to release retinol gradually to help reduce common retinoid side effects like redness and flaking. Still, some users may experience temporary dryness as skin adjusts; modifying frequency or using a richer moisturizer can help.

• Controlled release: designed to improve tolerability compared with immediate-release formulas.
• Adjustment period: reduce application frequency if irritation appears.
• Supportive care: use hydrating moisturizers and gentle cleansers to minimize dryness.

What makes Obagi360 Retinol 1.0 different from other retinol creams?

This formula emphasizes a high-retinol concentration combined with an entrapped delivery system to balance potency and comfort. Backed by Obagi’s clinical testing and decades-long professional skincare history, it aims to deliver visible benefits while prioritizing dermatological tolerability.

• Entrapped delivery technology for gradual release.
• High concentration retinol to target lines and uneven texture.
• Dermatologist tested and part of a clinically validated product line.

Who is this for: Obagi360 Retinol 1.0 is intended for adults seeking a potent, physician-endorsed retinol to address fine lines, texture irregularities, and uneven tone. It suits users who have tolerated lower-strength retinols and want a controlled-release, higher-strength option; those with very sensitive skin should introduce it cautiously or consult a clinician first.

• Renew Your Skin: Minimize visible signs of skin aging with our highly effective retinol cream designed with an entrapped retinol delivery system that gradually and gently releases ingredients with minimal irritation
• High Concentration Retinol: Our unique formula features Retinol, a retinoid that has been shown to reduce the appearance of fine lines and wrinkles, smooth skin texture, and improve overall skin tone.
• Clinically Proven: 90% saw an improvement in facial skin appearance in 3 weeks, 88% saw an improvement in skin texture; Data on file at Obagi Cosmeceuticals LLC
• Dermatologist Tested, Physician Endorsed: Our portfolio of products is dermatologist tested and physician endorsed; that’s why professionals trust us to provide superior skincare for their patients
• 35 Years of Transformational Skincare: From being the first to clinically test our products on all skin types & tones, to setting the standard for medical-grade skincare, we’re proud to bring you effective & transformative solutions for every step of your skincare journey

Ingredients

Water (aqua), caprylic/capric triglyceride, glyceryl stearate, cyclopentasiloxane, butylene glycol, stearic acid, butyrospermum parkii (shea) butter, polysorbate 60, stearyl alcohol, glycerin, allyl methacrylates crosspolymer, retinol, polysorbate 20, dimethicone, simmondsia, chinensis (jojoba) seed oil, chamomilla recutita (matricaria) flower extract, hypericum perforatum flower extract, malva sylvestris (mallow) flower, extract salvia officinalis (sage) leaf extract, sambucus nigra flower extract, cyclohexasiloxane, sorbitol, tocopheryl acetate, ascorbic acid, ubiquinone, sodium hyaluronate, propylene glycol, BHT, bisabolol, dimethicone/vinyl dimethicone crosspolymer, dipotassium glycyrrhizate, disodium EDTA, triethanolamine, carbomer, glyceryl acrylate/acrylic acid copolymer, caprylyl glycol, ethylhexylglycerin, hexylene glycol, phenoxyethanol