Obagi Medical 360 Retinol 0.5 Cream 1 oz — Controlled-Release Retinol for Smoother, Even Tone

Obagi 360 Retinol 0.5 Technology is a dermatologist-developed, cream-based retinol that releases retinol slowly to help reduce the look of fine lines, wrinkles, and uneven texture with minimal irritation.

This 1 oz treatment combines an entrapped retinol delivery system with a moisturizing, cream base so retinol is released gradually. That design helps maximize visible smoothing and tone improvement while reducing the sting and redness sometimes associated with retinoids. The formula is positioned for daily skincare routines and is part of Obagi Medical’s clinical lineage of physician-endorsed products.

How does the entrapped retinol delivery system make retinol gentler?

The entrapped delivery system surrounds retinol molecules so they are released over time rather than delivered all at once. Slower release lowers peak concentrations on the skin, reducing the likelihood of irritation while preserving efficacy. This makes it a practical step-in option for people who want retinol benefits without significant sensitivity.

• Controlled-release retinol for steadier activity
• Cream base to support skin hydration
• Formulated to reduce typical retinol redness and peeling

What skin concerns can this 0.5% retinol address?

This mid-strength retinol is aimed at reducing visible signs of aging such as fine lines, mild wrinkles, and rough or uneven texture. Over weeks of consistent use, skin may look smoother and tone can appear more even. Results vary by individual and depend on routine consistency and sun protection.

• Minimizes fine lines and surface wrinkles
• Improves skin texture and smoothness
• Helps even skin tone when used with sunscreen

Is Obagi 360 Retinol 0.5 suitable for sensitive or beginner retinol users?

Yes — the product is formulated for tolerability and can work for those new to retinol who need a balanced strength. Because the cream base and delivery system moderate release, many users experience fewer irritation symptoms compared with traditional retinol serums. Still, start slowly and follow recommended frequency to assess tolerance.

• Cream formulation reduces dryness versus alcohol-based serums
• Designed for all skin types, including sensitive skin
• Suitable as a stepping stone before higher-retinol products

How should Obagi 360 Retinol 0.5 fit into my skincare routine?

Apply retinol at night after cleansing and before heavier creams or oils. Begin using 1–2 times per week, then increase frequency as tolerated to nightly use. Always pair retinol with daily broad-spectrum sunscreen during daytime to protect newly renewed skin.

• Nighttime application after clean, dry skin
• Start gradually, then increase frequency based on tolerance
• Use daily SPF in the morning to protect skin

Who is this for: Obagi 360 Retinol 0.5 Technology is aimed at adults seeking a medical-grade, moderately potent retinol that balances visible anti-aging benefits with a formulation designed to reduce irritation. It suits first-time retinol users, people with sensitive skin who want retinoid results, and anyone looking to incorporate a dermatologist-tested retinol into a daily nighttime skincare routine. If you have specific skin conditions or are using prescription-strength products, consult a skincare professional before introducing retinol.

Ingredients

Water (aqua), caprylic/capric triglyceride, glyceryl stearate, cyclopentasiloxane, butylene glycol, stearic acid, butyrospermum parkii (shea) butter, polysorbate 60, stearyl alcohol, glycerin, retinol, polysorbate 20, dimethicone, carthamus tinctorius (safflower) seed oil, calendula officinalis flower extract, camellia oleifera leaf extract, camellia sinensis leaf extract, chamomilla recutita (matricaria) flower-extract, tocopheryl acetate, ascorbic acid, sodium hyaluronate, cyclohexasiloxane, sorbitol, BHT, bisabolol, allyl methacrylates crosspolymer, dimethicone/vinyl dimethicone crosspolymer, dipotassium glycyrrhizate, disodium EDTA, triethanolamine, carbomer, glyceryl acrylate/acrylic acid copolymer, caprylyl glycol, ethylhexylglycerin, hexylene glycol, phenoxyethanol