NIOXIN System 4 Shampoo & Conditioner Prepack 33.8 fl oz — For Color-Treated, Damaged & Thinning Hair with Niacinamide

Nioxin System 4 Shampoo & Conditioner Prepack is a two-step professional regimen formulated to cleanse, strengthen and visibly thicken color-treated, dry or damaged hair with progressed thinning.

This duo pairs a derma-purifying cleanser with a lightweight, density-protecting conditioner to remove buildup, protect hair color and reinforce each strand’s structure. Infused with niacinamide, biotin and antioxidant-rich botanicals, the system prepares the scalp and hair for fuller-looking results while addressing moisture balance and breakage resistance. Pumps are included for easy dispensing in the 33.8 fl oz bottles.

How does System 4 help hair that has been color-treated and damaged?

System 4 uses targeted surfactants and Pro-Color Shield technology to lift sebum, styling residue and pollutants that weigh hair down and dull color. The conditioner restores moisture without heavy weight, helping strands look thicker and color stay vibrant.

• Pro-Color Shield helps protect hair dye from fading.
• Formulation removes excess oils and debris that clog follicles.
• Amp technology balances hydration to avoid limp, weighted hair.
• Lightweight conditioning restores resilience without residue.

What ingredients support thicker-looking hair in this kit?

Key actives such as niacinamide and biotin support scalp function and strengthen hair at the shaft, while antioxidants and botanicals help protect against environmental stressors. Together they promote improved density perception and reduce the appearance of breakage over time.

• Niacinamide helps maintain a healthy scalp environment.
• Biotin supports hair strength and reduces snap during styling.
• Antioxidant botanicals protect against UV and pollution damage.
• Professional-grade cleansers remove follicle-clogging residue.

How quickly can you expect visible changes and what does clinical testing show?

Clinical and consumer testing indicate noticeable improvements in thickness and fullness within approximately 30 days for many users, when used as directed. Results depend on individual hair condition and consistency of use; the system is designed to strengthen strands and minimize breakage to improve overall appearance.

• Visible thickening reported by a majority of participants in studies.
• Increases in perceived hair density and fullness with regular use.
• Reduces breakage by reinforcing hair resilience and moisture balance.
• Designed as the first two steps of the three-part Nioxin regimen.

How should you use this shampoo and conditioner for best results?

Apply the cleanser to wet hair, massage into the scalp to lift oils and residue, then rinse thoroughly. Follow with the Scalp Therapy Conditioner, focusing on mid-lengths to ends, leave for a minute, and rinse; use consistently and follow with the System 4 scalp treatment if available.

• Use on wet hair; massage cleanser into the scalp to remove buildup.
• Apply conditioner from mid-lengths to ends; avoid heavy root application.
• Rinse thoroughly and repeat as needed for a second cleanse in heavy buildup cases.
• Pair with the full Nioxin three-part regimen for optimal outcomes.

Who is this for: Nioxin System 4 Prepack is intended for people with color-treated, dry or damaged hair experiencing progressed thinning who want a salon-grade daily shampoo and conditioner set. It suits those seeking to reduce breakage, protect hair color and create a fuller-looking appearance without heavy, residue-prone formulas. This kit is not a medical treatment; it’s a cosmetic system designed to improve the visible density and manageability of weakened hair when used regularly.

Ingredients

Shampoo: WATER/EAU, SODIUM LAURETH SULFATE, SODIUM LAURYL SULFATE, CITRIC ACID, SODIUM CHLORIDE, PPG-2 HYDROXYETHYL COCO/ISOSTEARAMIDE, SODIUM CITRATE, SODIUM XYLENESULFONATE, SODIUM BENZOATE, SALICYLIC ACID, SODIUM HYDROXIDE, TETRASODIUM EDTA, MENTHA PIPERITA (PEPPERMINT) OIL, MENTHA ARVENSIS LEAF OIL, MENTHOL, TRISODIUM ETHYLENEDIAMINE DISUCCINATE, METHYLPARABEN, POLYQUATERNIUM-10, PROPYLENE GLYCOL, CAMELLIA SINENSIS LEAF EXTRACT, CYSTINE BIS-PG-PROPYL SILANETRIOL, BIOTIN, LECITHIN, NIACINAMIDE, PANTHENOL, TOCOPHERYL ACETATE, FOENICULUM VULGARE (FENNEL) FRUIT EXTRACT, SODIUM ACETATE, ISOPROPYL ALCOHOL, YELLOW 5, YEAST EXTRACT/ EXTRAIT DE LEVURE, ACER SACCHARUM (SUGAR MAPLE) EXTRACT, CITRUS LIMON (LEMON) PEEL EXTRACT, SACCHARUM OFFICINARUM EXTRACT, VACCINIUM MYRTILLUS LEAF EXTRACT, BLUE 1, CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT, RED 33, POTASSIUM SORBATE. Conditioner: Aqua/Water/Eau, Cetyl Alcohol, Stearamidopropyl Dimethylamine, Stearyl Alcohol, Quaternium-18, Phenoxyethanol, Benzyl Alcohol, Cetearyl Alcohol, Hydroxypropyl Guar, Glyceryl Stearate, Oleyl Alcohol, Propylparaben, Polysorbate 60, Mentha Piperita (Peppermint) Oil, Mentha Arvensis Leaf Oil, Menthol, Propylene Glycol, Methylparaben, EDTA, Hydroxyethylcellulose, Citric Acid, Camellia Sinensis Leaf Extract, Quaternium-80, Cystine Bis-PG-Propyl Silanetriol, Biotin, Lecithin, Niacinamide, Panthenol, Tocopheryl Acetate, Foeniculum Vulgare (Fennel) Fruit Extract, Acer Saccharum (Sugar Maple) Extract, Citrus Limon (Lemon) Peel Extract, Saccharum Officinarum/Sugar Cane Extract/Extrait de canne à sucre, Vaccinium Myrtillus Leaf Extract, Faex Extract/Yeast Extract/Extrait de levure, Citrus Aurantium Dulcis (Orange) Fruit Extract, Maltodextrin, Blue 1 (CI 42090), Potassium Sorbate, Sodium Benzoate, Ethylparaben, Butylparaben