Nioxin Scalp + Hair Thickening System 2 Shampoo — 10.1 fl oz for Natural/Untreated Hair with Niacinamide & Biotin

Nioxin Scalp + Hair Thickening System 2 Shampoo is a salon-grade cleanser formulated to deeply remove buildup and help hair look thicker and fuller for natural or untreated hair with progressed thinning.

This professional-strength shampoo is the first step in Nioxin's three-part System 2 regimen, developed to address natural hair showing signs of progressed thinning. Its Activ-Renewal technology targets sebum, fatty acids and environmental residues that can weigh hair down and clog follicles, while niacinamide and biotin help support hair resilience and surface texture. Use daily with the matching conditioner and scalp treatment for best visible results.

How does this shampoo prepare the scalp and hair for thicker-looking results?

The cleanser removes excess oils and topical residues that accumulate on the scalp and strand, giving subsequent treatments better access to the hair root and shaft. By clearing the environment around the follicle, the scalp is left cleaner and better primed for conditioning and topical thickening actives.

• Deep-acting formula lifts sebum, fatty acids and environmental buildup
• Prepares hair cuticle for conditioning and treatment absorption
• Supports a healthier scalp environment for routine use

What ingredients help strengthen hair in System 2?

Nioxin System 2 combines niacinamide and biotin with botanical antioxidants to help reinforce hair surface structure and improve manageability. These components are selected to enhance strand strength and reduce visible breakage without harsh stripping.

• Niacinamide promotes a refreshed scalp feeling and balanced appearance
• Biotin helps support hair’s structural resilience
• Antioxidant botanicals protect against environmental stressors

When will I see a difference and how should I use it?

Many users report visible improvement in fullness and density within about 30 days when following the full three-step regimen. For optimal outcomes, apply to wet hair, massage into the scalp and hair for approximately one minute, then rinse thoroughly and follow with System 2 conditioner and scalp treatment.

• Daily use recommended for consistent results
• Massage for at least one minute to activate cleansing agents
• Pair with System 2 Scalp Therapy Conditioner and treatment for best effect

Is this shampoo suitable for my hair type and thinning level?

System 2 is specifically formulated for natural or untreated hair experiencing progressed thinning; it targets hair that needs both cleansing strength and gentle care. If your hair is color-treated or chemically altered, consider a Nioxin system tailored for treated hair types.

• Designed for natural, untreated hair with noticeable thinning
• Not ideal for chemically treated or heavily processed hair
• Safe for daily use as part of a salon-grade routine

Who is this for: Nioxin System 2 Scalp + Hair Thickening Shampoo is made for people with natural or untreated hair who are noticing progressed thinning and want a professional, scalp-focused cleansing step. It suits anyone seeking to remove scalp buildup, strengthen strands, and improve the look of fullness when used as part of the three-step Nioxin program.

Features

• 85% of consumers noticed a thickening effect, 80% noticed increased hair density and fullness
• Clinically designed to add thickness and amplifies hair structure in approximately 30 days when used with the full kit
• Activ-Renewal technology removes sebum, fatty acids and environmental residue
• Infused with niacinamide, biotin, botanicals, antioxidants and UV protection to nourish scalp and hair

Ingredients

Water/Eau, Sodium Laureth Sulfate, Sodium Lauryl Sulfate, Cocamidopropyl Betaine, Sodium Citrate, Sodium Xylenesulfonate, Sodium Chloride, Cocamide MEA, Sodium Benzoate, Citric Acid, Salicylic Acid, Mentha Piperita (Peppermint) Oil, Mentha Arvensis Leaf Oil, Menthol, Tetrasodium EDTA, Sodium Hydroxide, Methylparaben, Propylene Glycol, Camellia Sinensis Leaf Extract, Cystine Bis-PG-Propyl Silanetriol, Biotin, Lecithin, Niacinamide, Panthenol, Tocopheryl Acetate, Citrus Paradisi (Grapefruit) Peel Extract, Humulus Lupulus (Hops) Flower Extract, Urtica Dioica (Nettle) Leaf Extract, Yellow 5, Yeast Extract, Acer Saccharum (Sugar Maple) Extract, Citrus Limon (Lemon) Peel Extract, Saccharum Officinarum Extract, Vaccinium Myrtillus Leaf Extract, Blue 1, Citrus Aurantium Dulcis (Orange) Fruit Extract, Red 33, Potassium Sorbate.