Mustela Baby Diaper Rash Cream — 3.8 oz Fragrance-Free Zinc Oxide, 98% Plant-Based Soothing & Protective

Mustela Baby Diaper Rash Cream 123 is a fragrance-free, 3-in-1 diaper cream that helps prevent, soothe and support recovery of delicate diaper-area skin.

Designed for newborns and up, this 3.8 oz cream blends 98% plant-based ingredients with zinc oxide and the brand's patented Avocado Perseose to form a protective, comforting layer on baby’s skin. The formula is hypoallergenic, free from parabens, phthalates and phenoxyethanol, and has been tested under pediatric and dermatological control. It’s intended for use at every diaper change to minimize irritation and help the skin recover.

How does this cream help at each diaper change?

Applied liberally, the cream creates a physical barrier that helps shield skin from moisture and irritants while delivering nourishing plant-derived actives. It combines immediate soothing components with repairing botanical oils to support the skin barrier over time.

• Zinc oxide forms a protective, moisture-resistant layer.
• Sunflower Oil Distillate helps replenish and support the skin barrier.
• Oxeoline of Alcacea provides calming support to reduce visible redness.
• Use at each diaper change, especially overnight, for consistent care.

Is this safe for newborn and sensitive skin?

The formula is created for delicate baby skin and is labeled newborn-safe. It is hypoallergenic and was evaluated under pediatric and dermatological control to reduce the chance of irritation.

• Fragrance-free to minimize sensory irritation.
• Free from parabens, phthalates and phenoxyethanol.
• Designed to limit allergic reactions with careful ingredient selection.

What exactly is inside the cream, and how do those ingredients work?

The product uses a combination of mostly plant-based ingredients plus zinc oxide to provide protection, soothe irritation and help restore skin. Mustela’s patented Avocado Perseose is included to help maintain the integrity of the baby’s skin barrier.

• Avocado Perseose: patented plant-derived ingredient that supports skin’s natural defenses.
• Sunflower Oil Distillate: replenishes lipids and supports repair.
• Zinc Oxide: mineral-based barrier to protect skin from moisture exposure.
• Oxeoline of Alcacea: calming botanical extract that helps reduce redness.

How should I use the cream for the best results?

Apply liberally at every diaper change to clean, dry skin, paying attention to areas prone to chafing and moisture. Regular application helps both soothe existing irritation and reduce the likelihood of recurrence.

• Cleanse and pat the diaper area dry before application.
• Spread a thin, even layer across affected skin; more at bedtime or long stretches.
• Use consistently during diaper changes until skin appears restored.

Who is this for? Parents and caregivers seeking a gentle, clinically-assessed diaper cream for daily use will find this product suited for newborns and older infants who need regular barrier protection and calming care. It fits families prioritizing mostly plant-based ingredients, fragrance-free formulations, and products tested with pediatric and dermatological oversight. Ideal for those who want a single, multi-purpose cream to prevent, relieve and support skin recovery during routine diapering.

Ingredients

ZINC OXIDE (9.9%), BEESWAX, CAPRYLIC/CAPRIC TRIGLYCERIDE, CAPRYLOYL GLYCINE, CAPRYLYL GLYCOL, COCO-CAPRYLATE/CAPRATE, ETHYL LINOLEATE, GLYCERIN, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES, LEVULINIC ACID, MAGNESIUM SULFATE, PERSEA GRATISSIMA (AVOCADO) FRUIT EXTRACT, PERSEA GRATISSIMA (AVOCADO) OIL, POLYGLYCERYL-2-DIPOLY - HYDROXYSTEARATE, POLYGLYCERYL-3 DIISOSTEARATE, PROPYLENE CARBONATE, SODIUM LEVULINATE, STEARALKONIUM HECTORITE, UNDECYL DIMETHYL OXAZOLINE, AQUA/WATER/EAU