Mary&May Spicule Retinol PDRN Cream 0.53 oz — Micro-Spicules & Gentle Retinol for Sensitive Skin

Mary&May Spicule Retinol PDRN Cream is a concentrated Korean night booster that uses marine micro-spicules plus encapsulated retinol and soothing PDRN to refine pores, smooth texture, and support a gentle retinol introduction for sensitive skin.

This compact 0.53 oz jar combines roughly 2,000 ppm marine micro-spicules with 1,000 ppm nano liposome retinol and a calming CICA + PDRN complex so active ingredients penetrate the skin more effectively while helping reduce the usual irritation associated with retinol. The formula also includes niacinamide and a 4x barrier-support blend—panthenol, ceramide NP, hyaluronic acid, and allantoin—delivered fragrance-free and dermatologist-tested. A light tingling on first contact is expected as the micro-spicules create tiny channels for faster absorption.

How does the micro-spicule delivery make a difference?

The marine micro-spicules are microscopic, rigid particles (80–300 µm) that lightly abrade the skin surface, creating micro-channels so the cream's active ingredients penetrate more than they would from a standard moisturizer. That targeted delivery helps the retinol booster and supporting actives work where texture and pore appearance matter most without relying on higher retinol concentrations.

• Approximately 200,000 micro-spicules per jar for targeted delivery.
• Spicule size about 1/40th the diameter of a pore for precise action.
• Creates fine channels to improve ingredient absorption, not deep abrasion.

Is the retinol safe for sensitive or retinol-new skin?

This product uses nano liposome-encapsulated retinol to slow release and reduce immediate irritation, and the formula pairs that retinol with Centella (CICA), PDRN, and barrier-supporting humectants. It’s designed for a cautious ramp-up—start 2–3 nights weekly and increase only as tolerated—avoiding concurrent strong acids or vitamin C on the same nights.

• Encapsulated retinol for gentler, sustained delivery.
• CICA + PDRN soothe and cushion during adjustment phases.
• Guided use: pea-sized amount, nights only, sunscreen required by day.

What skin concerns can this cream target effectively?

Mary&May Spicule Retinol PDRN Cream focuses on visible texture, enlarged pores, and the early signs of aging like fine lines by combining physical micro-resurfacing with a slow-release retinol booster and barrier-supportive ingredients. Niacinamide helps brighten and even tone while hydrating actives maintain comfort so you can stay consistent.

• Refines the look of enlarged pores and surface roughness.
• Visibly smooths fine lines with ongoing use and retinol delivery.
• Supports hydration and barrier resilience to minimize peeling and dryness.

How should I incorporate this into my routine for best results?

Use it as the final nighttime step after cleansing and lightweight serums. Begin with 2–3 nights per week, applying a pea-sized amount over the face, and increase frequency only as your skin builds tolerance. Avoid mixing with AHA/BHA or vitamin C on the same night and prioritize daily sunscreen while using any retinol product.

• Apply a pea-sized amount at night as your last step.
• Start slowly: 2–3 nights weekly, then increase as tolerated.
• Do not use with AHA/BHA or vitamin C simultaneously; use SPF daytime.

Who is this for? This jar is intended for adults looking to refine pores, improve skin texture, and introduce retinol with a gentler delivery system—especially those with sensitive or reactive skin who need barrier support while using active ingredients. Because the product is concentrated and designed for incremental use, the 0.53 oz size suits targeted treatment periods, trialing retinol for the first time, or travel-friendly booster use.

Ingredients

Aqua(Water), Methylpropanediol, Glycerin, 1,2-Hexanediol, Niacinamide, Panthenol, Caprylic/Capric Triglyceride, Polypropylsilsesquioxane, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate/VP Copolymer, Glyceryl Stearate, Cetyl Ethylhexanoate, Vinyl Dimethicone, Macadamia Ternifolia Seed Oil, Brassica Campestris (Rapeseed) Sterols, Polyglyceryl-10 Laurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12- 20 Alkyl Glucoside, Arginine, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Cholesterol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrolyzed Sponge, Polyisobutene, Gardenia Florida Fruit Extract, Tocopherol, Allantoin, Ethylhexylglycerin, Butyrospermum Parkii (Shea) Butter, Retinol, Xanthan Gum, Hydrogenated Lecithin, Sodium Hyaluronate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Adenosine, Dextrin, Helianthus Annuus (Sunflower) Seed Oil, Lauryl Glucoside, Polyglutamic Acid, Polyglyceryl-6 Laurate, Disodium EDTA, Ceramide NP, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Myristyl Glucoside, Stearic Acid, Benzotriazolyl Dodecyl p-Cresol, Glyceryl Acrylate/Acrylic Acid Copolymer, Oleic Acid, PVM/MA Copolymer, Beta-Carotene, Sodium DNA