Mary&May Spicule Collagen PDRN Cream 0.53 oz - Targeted Plumping & Barrier Repair with Marine Spicules

Mary&May Spicule Collagen PDRN Cream is an intensive 15 g Korean skin treatment that uses marine micro-spicules, PDRN and French marine collagen to target firmness, plumping and barrier comfort.

Designed as a concentrated care step rather than an everyday all-over cream, this petite jar combines micro-delivery technology with soothing actives to improve how serums and creams absorb. The formula pairs visible plumping agents with a calming barrier complex so sensitive or reactive skin can receive concentrated support. Apply sparingly at night to target areas for gradual lifting and refreshed texture.

How does the spicule delivery system improve ingredient absorption?

Tiny natural marine spicules create micro-pathways on the skin surface that help active ingredients penetrate more effectively. The mild tingling you may feel is a normal indication that delivery is occurring, not damage. Because the spicules are naturally derived and used in minimal amounts, the effect is targeted rather than abrasive.

• Contains 90,000+ marine micro-spicules to enhance topical delivery
• Mild tingling is expected — a sign of active absorption
• Intended for focal application, not whole-face daily use

What do PDRN and French marine collagen do in this cream?

PDRN (polydeoxyribonucleotide) supports skin recovery pathways while French marine collagen adds concentrated proteins aimed at improving visible volume and elasticity. Together they work with the spicule system to reach deeper layers more effectively than collagen alone. The combination is formulated to help the complexion appear plumper and more resilient over time.

• PDRN for skin recovery-supporting activity
• French marine collagen to enhance visible plumping
• Synergy designed for improved firmness over isolated collagen

Is this safe for sensitive skin and how should I use it?

The cream includes a soothing barrier repair complex—Centella Asiatica, 2% panthenol, Ceramide NP, hyaluronic acid and allantoin—designed to calm and hydrate. Because the product is concentrated and uses micro-spicules, start slowly: apply a pea-sized amount to targeted areas 2–3 nights per week, then increase frequency as tolerated. If irritation occurs, reduce use or pause and consult a skincare professional.

• Gentle-support ingredients to comfort sensitive skin
• Start 2–3 nights weekly; use as a targeted spot treatment
• Not intended as a daily full-face moisturizer

What results can I expect and when might they appear?

Users report improved appearance of plumpness, firmer-looking texture and enhanced barrier comfort when used as directed. Because it is an intensive, short-contact treatment, visible changes typically appear over several weeks of consistent, targeted use. Results depend on individual skin condition and routine consistency.

• Designed to reduce the look of fine lines and support bounce
• May leave skin feeling lifted and refreshed after repeated use
• Best used as the final step in a nighttime routine on focused areas

Who is this for: Mary&May Spicule Collagen PDRN Cream is geared toward people seeking a small, high-potency corrective step for areas that need plumping or firmness—smile lines, nasolabial folds, forehead lines and targeted cheeks. It suits those with sensitive or reactive skin who want a scientifically minded Korean treatment with built-in soothing ingredients, provided they follow the recommended gradual introduction and spot-focused application. Not recommended as a daily whole-face moisturizer; ideal for anyone wanting a concentrated boost to an existing skincare routine.

Ingredients

Aqua(Water), Methylpropanediol, Glycerin, 1,2-Hexanediol, Panthenol, Niacinamide, Caprylic/Capric Triglyceride, Polypropylsilsesquioxane, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate/VP Copolymer, Glyceryl Stearate, Hydrolyzed Collagen, Cetyl Ethylhexanoate, Vinyl Dimethicone, Macadamia Ternifolia Seed Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12-20 Alkyl Glucoside, Arginine, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Brassica Campestris (Rapeseed) Sterols, Polyglyceryl-10 Laurate, Polyisobutene, Dextrin, Tocopherol, Allantoin, Ethylhexylglycerin, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Cholesterol, Hydrolyzed Sponge, Gardenia Florida Fruit Extract, Xanthan Gum, Butyrospermum Parkii (Shea) Butter, Adenosine, Lauryl Glucoside, Hydrogenated Lecithin, Sodium Hyaluronate, Polyglyceryl- 6 Laurate, Disodium EDTA, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Polyglutamic Acid, Myristyl Glucoside, Ceramide NP, Glyceryl Acrylate/Acrylic Acid Copolymer, Stearic Acid, PVM/MA Copolymer, Oleic Acid, Sodium Guaiazulene Sulfonate, Sodium DNA