IsisPharma Neotone Pigmentation Spots Night Serum — 30ml, glycolic + salicylic exfoliation & melanin-inhibitors

IsisPharma Neotone Pigmentation Spots Serum is a targeted night-time serum formulated to visibly reduce and prevent dark spots by combining melanin-regulating actives with gentle exfoliants.

This lightweight serum concentrates several complementary ingredients to tackle both existing pigmentation and the processes that create new dark spots. It combines exfoliating acids to accelerate removal of pigmented cells with molecules that slow melanogenesis and block melanin formation, all in a non-comedogenic formula tested under dermatological control. Intended for evening use, Neotone can be layered under your usual night cream or used as directed by a healthcare professional.

How does Neotone address existing dark spots?

The serum contains glycolic and salicylic acids that help lift and remove pigmented, outer skin cells, accelerating the skin’s natural renewal. Regular use promotes a more even surface tone while improving texture without heavy occlusion.

• Glycolic acid: chemical exfoliant that aids removal of pigmented cells.
• Salicylic acid: oil-soluble exfoliant that helps refine skin texture.
• Non-comedogenic base: unclogged pores while treating spots.

What ingredients prevent new pigmentation from forming?

Neotone integrates actives that interfere with melanin production and distribution. Diacetyl boldine and a trio of licorice, α-arbutin, and vitamin C derivatives work through different mechanisms to reduce melanin synthesis and limit visible darkening over time.

• Diacetyl boldine: helps inhibit the early steps of melanin appearance.
• Licorice + α-arbutin: attenuate tyrosinase-related pigment pathways.
• Ascorbic acid (vitamin C): antioxidant support to brighten and protect.

How and when should I apply this serum for best results?

Apply Neotone each night to the areas of concern, either alone or before your regular night moisturizer, avoiding the eye contour. Because it contains exfoliating acids, pair nightly use with daytime sun protection to protect renewed skin from UV-induced pigment rebound.

• Frequency: nightly on hyperpigmented patches or as directed by a dermatologist.
• Application: smooth a small amount over target zones; avoid eyes.
• Sun care: use daily SPF in the morning to prevent new pigmentation.

Is the formula suitable for sensitive or acne-prone skin?

The serum is non-comedogenic and dermatologically tested, making it suitable for skin prone to congestion. Those with sensitive skin should introduce it gradually and consult a professional if irritation occurs, because acids and active inhibitors can be sensitizing for some individuals.

• Non-comedogenic: designed not to block pores.
• Dermatologically tested: assessed under professional supervision.
• Patch-test recommended: start slowly if you have reactive skin.

Who is this for: IsisPharma Neotone Pigmentation Spots Serum is aimed at people concerned with localized hyperpigmentation—age spots, sun spots, post-inflammatory marks, and uneven tone—who want a night-time, active-based solution. It suits those comfortable using chemical exfoliants and melanin-regulating actives, and who will pair treatment with daily sun protection. If you have severe pigmentation or active skin conditions, consult a dermatologist to integrate Neotone into a broader care plan.