Eau Thermale Avène Cicalfate+ Intensive Restorative Serum — lightweight, fragrance-free barrier repair with Pro-Vitamin B5

Avène Cicalfate+ Intensive Restorative Serum is a lightweight, fast-absorbing face serum that soothes sensitivity and fortifies the skin barrier with TRP-Regulin™ and Pro-Vitamin B5.

Designed for sensitive and reactive skin, this fragrance-free serum combines dermatologist-grade actives to calm discomfort, hydrate, and reinforce the skin’s natural defenses. The formula absorbs quickly without leaving a residue, making it suitable for morning and evening routines and for layering under moisturizers or sunscreen. Clinical testing shows barrier restoration benefits quickly, and the product emphasizes high natural-origin content for gentle efficacy.

How does this serum calm tight, reactive skin?

TRP-Regulin™ targets mechanisms linked to sensitivity, helping reduce sensations of tightness and irritation. The serum’s lightweight base spreads easily and delivers the active ingredient where it’s needed for rapid soothing without heavy emollients.

• TRP-Regulin™ soothes sensations of discomfort and reactivity
• Fast absorption prevents greasy buildup on sensitive skin
• Fragrance-free formula minimizes irritation risk

What strengthens the skin barrier and how quickly does it work?

Pro-Vitamin B5 (panthenol) helps reinforce the skin’s lipid matrix and supports moisturization to reduce transepidermal water loss. A pharmacological test under hydric stress showed measurable improvement in barrier function in as little as one day.

• Pro-Vitamin B5 hydrates and supports barrier repair
• Clinically demonstrated barrier benefits in short-term testing
• Supports long-term resilience when used consistently

How should I use it in my daily skincare routine?

Apply a few drops onto cleansed skin, morning and evening, before your moisturizer and sunscreen. Its light texture makes it ideal for layering under creams or makeup without pilling.

• Use on cleansed face and neck, 1–2 drops per application
• Layer under moisturizer and SPF during the day
• Safe for everyday use on sensitive skin types

What are the key formula highlights and safety features?

The serum is fragrance-free and formulated for tolerance by sensitive skin. With 96% ingredients of natural origin and a focus on clinically backed actives, it balances efficacy with gentle care.

• Fragrance-free and suitable for sensitive skin
• 96% ingredients of natural origin for mildness
• Dermatologist-developed and clinically tested

Who is this for: Avène Cicalfate+ Intensive Restorative Serum is aimed at anyone experiencing sensitivity, dryness-related tightness, or a weakened skin barrier—especially those who prefer fragrance-free, fast-absorbing textures. It suits all skin types, including reactive and easily irritated skin, and works well for people who need a calming, barrier-supportive step they can use daily within a multi-product routine.

Key features:

• Immediately soothes feelings of tightness and discomfort associated with dryness
• Moisturizes for 24 hours
• 96% Ingredients of natural origin

Ingredients

Avene Thermal Spring Water (Avene Aqua), Glycerin, Pentylene Glycol Propanediol 1.2-Hexanediol, Panthenol 4-T-Butylcyclohexanol Octyldodecanol Pantolactone, Betaine, Citric Acid, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 60, Sodium Citrate, Sorbitan Isostearate, Water (Aqua), Xanthan Gum.