Dr. Denese Triple Strength Wrinkle Smoother Night Cream 3.4 oz — Triple Peptides, Retinol & Hyaluronic Hydration

Dr. Denese Triple Strength Wrinkle Smoother is a nighttime facial cream that combines a triple-peptide complex with retinol and hyaluronic acid to hydrate and visibly refine lines while you sleep.

This advanced night treatment from Dr. Denese SkinScience is formulated to deliver concentrated peptide support, moisture-binding hyaluronic acid, and retinol in a paraben-free, cruelty-free base. The rich yet non-greasy texture is designed for nightly use to help improve surface texture and hydration over time. Dermatologist-developed ingredients focus on firmness and smoothness without heavy residue, making it suitable for an evening skin routine.

How does this cream target wrinkles and texture overnight?

The formula uses a triple peptide complex to support visible refinement of fine lines and surface irregularities. Retinol helps encourage skin turnover, while hyaluronic acid pulls and locks in moisture for a plump appearance. Together these actives work during the skin’s natural overnight repair cycle to improve tone and texture.

• Triple peptide blend to support visible smoothing of line depth
• Retinol to encourage gentle skin renewal
• Hyaluronic acid for immediate and sustained hydration
• Glycerin and squalane to reinforce barrier and comfort

Will this feel heavy or greasy on my skin?

The night cream is formulated with a luxurious yet lightweight texture that absorbs without leaving a greasy film. Moisturizing agents like squalane and glycerin provide lasting softness while keeping the finish breathable. Most users report comfortable overnight wear and refreshed skin come morning.

• Non-greasy finish for comfortable overnight wear
• Balanced emollients for lasting softness without clogging
• Suitable for layering under daytime products when used sparingly

How soon can I expect to see results and how should I use it?

Visible improvements in texture and hydration often appear with consistent nightly use over several weeks. For best results, apply a pea-sized amount to clean, dry face and neck after cleansing, avoiding immediate eye contact. Use sunscreen during daytime when incorporating retinol into your routine.

• Apply nightly to cleansed skin, a little goes a long way
• Expect progressive texture improvement with regular use
• Pair with daily SPF to protect renewed skin

What safety and ingredient standards does this product follow?

Dr. Denese formulates this cream without parabens, sulfates, or phthalates and does not test on animals. The product is dermatologist-developed, focusing on scientifically backed actives while maintaining a clean approach. As with any retinol-containing product, start gradually if you have sensitive skin and perform a patch test if concerned.

• Paraben-, sulfate-, and phthalate-free formulation
• Cruelty-free and dermatologist-developed
• Includes scientifically recognized ingredients like peptides, retinol, and hyaluronic acid

Who is this for? If you want a concentrated overnight moisturizer that blends peptide technology with hydrating and renewing ingredients, this cream is aimed at adults seeking smoother, more resilient-feeling skin. It’s suitable for those familiar with retinol or wanting targeted anti-aging support without heavy, greasy products. Not recommended for children; consult a dermatologist if you have severe sensitivity or specific skin conditions.

Ingredients

Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Acacia Decurrens/Jojoba/Sunflower Seed Wax/Polyglyceryl-3 Esters, Butylene Glycol, Glycereth-26, Squalane, Stearyl Olivate, Octyldodecyl Olivate, Di-C12-15 Alkyl Fumarate, Dimethicone, Stearic Acid, Palmitoyl Tripeptide-38, Palmitoyl Heptapeptide, Palmitoyl Tetrapeptide-7, Palmitoyl Oligopeptide, Pantothenic Acid Heptapeptide-Cu, Rhododendron Ferrugineum Leaf Cell Culture Extract, Globularia Cordifolia Callus Culture Extract, Foeniculum Vulgare (Fennel) Fruit Extract, Humulus Lupulus (Hops) Extract, Melissa Officinalis Leaf Extract, Viscum Album (Mistletoe) Leaf Extract, Chamomilla Recutita (Matricaria) Flower Extract, Achillea Millefolium Extract, Glycine Soja (Soybean) Sterols, Adenosine, Urea, Allantoin, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, Coco-Glucoside, Mica, Titanium Dioxide, Iron Oxides, Lecithin, Sodium Benzoate, Lactic Acid, Polysorbate 60, Carbomer, Polysorbate 20, Polymethyl Methacrylate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrogenated Lecithin, Dimethiconol, Polyglycerin-10 Distearate, Tocopheryl Acetate, Arginine, Citrus Paradisi (Grapefruit) Peel Extract, Hydroxypropyl Bislauamide MEA, Lactic Acid/Glycolic Acid Copolymer, Dextran, Disodium EDTA, Isomalt, Phenoxyethanol, Ethylhexylglycerin.