Colorescience Pep Up Collagen Renewal Face & Neck Treatment — 10-Peptide Serum with Hyaluronic Acid, Lightweight Hydration

Colorescience Pep Up Collagen Renewal is a daily face and neck treatment that uses a 10-peptide complex plus hyaluronic acid to support collagen and elastin production while delivering lasting hydration.

This lightweight, fast-absorbing serum from Colorescience combines a proprietary Decaplex-10 peptide blend with moisturizing and antioxidant ingredients to help skin look firmer, smoother, and more evenly textured over weeks of regular use. Formulated without parabens, phthalates, synthetic fragrance, talc, dyes, mineral oils or drying alcohols, the treatment is hypoallergenic and non-comedogenic, making it suitable for many skin types, including sensitive and dry skin.

How does Pep Up help improve firmness and reduce the appearance of lines?

The formula relies on signaling and carrier peptides to support the skin’s natural repair processes and encourage fibroblasts to produce collagen and elastin. Over time this can improve the look of laxity and reduce the visibility of fine lines by promoting structural support in the dermis.

• Decaplex-10: ten targeted peptides designed to stimulate collagen and elastin pathways.
• Clinical testing showed most participants saw improvement in laxity and fine lines within 4–8 weeks.
• Lightweight texture absorbs without leaving a heavy film, allowing layered skincare.

Will this treatment hydrate my skin enough to skip a moisturizer?

Pep Up contains hyaluronic acid and plant-derived emollients to deliver deep hydration and help retain moisture in the skin’s surface layers. For many users the hydration level is sufficient to forgo a separate moisturizer, though those with very dry skin may still prefer an additional emollient step at night.

• Hyaluronic acid attracts and binds water for immediate plumping and comfort.
• Plant-derived softeners smooth texture while supporting barrier function.
• Acts as a hydrating layer when applied to slightly damp, warmed skin for best absorption.

How should I include Pep Up in my skincare routine for best results?

Apply 1–2 pumps twice daily to clean, slightly moist face and neck after cleansing or toner to maximize absorption. Use consistently; clinical study participants began seeing measurable improvements in overall skin health by four weeks and more noticeable changes by eight weeks.

• Morning and evening: 1–2 pumps applied to face and neck after cleansing.
• Apply to warmed, slightly damp skin to improve peptide delivery and hydration.
• Safe to layer under sunscreen or other serums; non-comedogenic formula minimizes pore congestion.

Is Pep Up safe for sensitive skin and free from common irritants?

Colorescience formulates Pep Up without parabens, phthalates, synthetic fragrance, talc, dyes, mineral oils, drying alcohols, or chemical sunscreens, and the product is hypoallergenic and non-comedogenic. Its gentle peptide and hydrating profile makes it appropriate for sensitive and reactive skin types, though patch testing is recommended with any active product.

• Free from common irritants and fragrance to reduce sensitization risk.
• Hypoallergenic and non-comedogenic—designed to be gentle on reactive skin.
• Clinical testing on a broad participant group supports tolerability and measurable improvement.

Who is this for: Colorescience Pep Up Collagen Renewal Face & Neck Treatment is aimed at anyone wanting a science-forward peptide serum that targets early to moderate signs of aging while delivering strong hydration. It’s a good fit for people who prefer clinically-backed formulations, those seeking to smooth texture and reduce fine lines, and anyone looking to consolidate steps by using a hydrating peptide treatment that can sometimes replace a separate moisturizer.

Ingredients

Water/Aqua/Eau, Isoamyl Laurate, Glycerin, Polyacrylate-13, Polyisobutene, Sodium Hyaluronate, Pseudoalteromonas Ferment Extract, Tripeptide-1, Hexapeptide-2, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Copper Tripeptide-1, Tripeptide-10 Citrulline, Acetyl Tetrapeptide-9, sh-Oligopeptide-1, Dipeptide Diaminobutryroyl Benzlamide Diacetate, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Physalis Angulata Extract, Betaine, Tremella Fuciformis Sporocarp Extract, Tocopherol, Beta-Glucan, Avena Sativa (Oat) Kernal Extract, Glycine Soja (Soybean) Oil, Hydrogenated Lecithin, Mannitol, Polysorbate 20, Ethylhexylglycerin, Caprylhydroxamic Acid, Caprylyl Glycol, Carbomer, Sodium Lactate, Lecithin, Xanthum Gum, Triethanolamine, Butylene Glycol, Disodium EDTA, Sodium Oleate, Sorbitan Isostearate, Caprylic/Capric Triglyceride, Potassium Sorbate, Phenoxyethanol